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glutathione in ros Reactive oxygen species generation and the mechanistic antioxidative Condition:GD
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Results Chronic iron accumulation and GSH depletion remodel labile iron pools and induce ferritin expression Our experimental design employed two complementary stress paradigms: (1) chronic iron accumulation to model age-related brain iron overload and (2) chronic GSH depletion using buthionine sulfoximine (BSO) to investigate the role of GSH loss independent of exogenous iron, since preliminary observations suggested a mechanistic link between iron and GSH dysregulation
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Erythrocyte oxidative stress markers in children with sickle cell disease
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