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A systematic review of 35 prospective cohort studies assessing the association between vitamin B 12 status and cognitive deterioration in older individuals with or without dementia at baseline did not support a relationship between serum vitamin B 12 concentrations and cognitive decline, dementia, or Alzheimer’s disease (79)
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Managing side effects during dose escalation Gastrointestinal side effects are the most commonly reported adverse events with retatrutide, and they peak during the dose escalation period
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